After you complete the initial click and drag through the first chamber and the purple mist stops at the blockage, check the map. If you have not reached the white square outline with the mist, go to the menu and restart the level. Continuing the game to clear the second chamber is a waste of time. If you have reached the white outline, you will have a greater chance at making it to the end. Note: If you can line up pieces in large quantity, you can blow the whole field apart.
Rather than click the pieces one by one then double clicking the final piece, click and hold the first piece and drag the pointer on all pieces you want to make a chain with. After that, click the last piece of the chain. You will make the chains a lot faster.