When it's your turn to create a word for your buddy to solve, follow these hints:
Use the most uncommon letters in your pool Ever watch Wheel of Fortune? The most common letters are R, S, T, L, N, E. People will guess these letters, so try using letters they won't guess, like X, Q and X.
Never use the same letter twice If you use the same letter twice, you'll help the other player by giving him two letters for just one guess. Words are much harder to figure out if they don't have repeating letters.
Use an online anagram generator This is pretty lame but search for online anagram generators and type in your pool of letters to get a bunch of words that your letters can spell.
If the revealed letter given to you is an "E" in the second to last position, the last letter is most likely an "R", a "D", or an "S". Your opponent may be making a word like "trad-ER", "trad-ED", or "trad-ES". Conversely, when it's your turn to make a word, you may be able to stump your opponent by placing an "E" in the second to last position and making a word that ends in "-EM" or "-EN".
A good strategy is to create words that could easily be turned into other words by changing one or two letters. For example, D-R-I-N-K could easily be confused with B-R-I-N-K, B-L-I-N-K and B-L-I-N-D, among others. This will keep your opponents guessing even when they think they have it.
A drumroll sound effect plays when you're guessing a word and have just one letter left to guess. If there are still two or more spaces left when you hear this sound, you know that those two or more spaces are filled with the same letter. So if you see "L A - - E R S" and hear the drumroll you can guess the word is "L A D D E R S" and not "L A Y Z E R S."
Know the relationship between word length and the number of strikes your opponent receives, and use it to your advantage. For example, when constructing a four-letter word, do a mental check that there are enough words with similar letters to make the word last eight tries. You can be less diligent when creating longer words, but do try to swap out some tiles to change the word to a less common one where possible. The following is how many strikes you or your opponents will receive based on word length (four letters is the minimum you can play):