Make a text file named Plasmid.txt with a text editor and place it in the "System" folder in the game directory, which is typically "C:\Program Files\2K Games\BioShock\Content\System". In the "User.ini" file used in the "Cheat mode" section, bind the following command to any key
Edit the Plasmid.txt file you have just made with any of the following commands listed below. Once you are in the game, use the key you have bound to the "exec Plasmid.txt" line, then go to a gene bank to check out any new Tonics you have summoned. Higher level Plasmids seem to replace lower level ones automatically. All of the below entries are Tonics unless otherwise indicated. Note: Some codes require version 1.1.