Playing as Logan is recommended for this trick. Humans can use weapons, and so can you. However, when it comes down to a gunfight, you are both evenly matched. A good way to kill humans with minimal effort is to throw modded weapons. However, there are a number of exceptions. The weapon Must be a sharp weapon. Blunt weapons only damage them slightly. The military machete works best. The weapon must have either a Poison mod or a Shock mod. Fire will not do anything. Make sure you upgrade the weapon to at least level 3. You may want to mod a powerful weapon because it will have minimal affect against stronger humans. Keep your distance when throwing, and have plenty of ammunition. This is one reason why Logan is better for this, because thrown objects can come back to him. However, if you have a clear view of the target, throw the weapon and they will die instantly.