-When firstbuilding your hospital, set the game speed on slowest. This will give you plenty of time to build the hospital. Once you are done, select the option that will open your hospital. This will allow you open sooner than the other hospitals. Once you are done, set the game speed to fastest to start getting patients in.
-An excellent way to get started is to build all your rooms in the order of appearance (GP's Office, General Diagnosis, Psychiatry, etc.) and hire your reception desk and buy her a desk. Use a simple method to make sure all your patients are happy. For instance, in every room put one of every extra item in. In the GP's office put in a Bin, Plant, Fire Extinguisher, and Radiator. Every room you make, put in all the windows you can, as this does not cost much and makes your staff happier; not to mention it causes no problems. Putting in all the extra items not only makes your staff happier, but also gives you the added benefits (Having Bins means less littering, Fire Extinguishers cut down on machine breakdown, etc.) Once you make a couple rooms, start by buying ten benches and surround the GP's office with it, and any other spaces. Next, for every room you make, put a Soda Machine next to the door. When patients wait, they will eventually cave in and buy a soda. For every room other than the GP's office where you put ten benches, put three benches near each room for patients waiting there. If there is space and if desired, arrange ten Plants along a wall. Having these Plants makes the patients happier and healthier. Furnish the Staff Room and make it as big as possible. More amenities not only mean quick recoveries, but happier staff and better performance. For any Training Rooms you may be building, make them big by putting in only one desk, so that only one student is being taught. Fill whatever remaining space with skeletons and bookcases. This is a great way to give your trainee a super boost. If you have rat infestations, you will notice little mouse holes in your walls. Get a Soda Machine you have already bought and place it up against the wall with the hole. Then, return it to its former position. The mouse hole is now gone. This trick also works for litter. Get a Soda Machine and place it on the tile which has litter or vomit and it will disappears. Having specialist Handymen is recommended. For example, hire three Handymen when possible. Set one to do nothing but water plants, the other to clean up litter, and the third to tend to the machines. Since machines take awhile to break down, the one who does nothing but machines will assist the other handymen with their chores. Note: To set what the Handyman should do more of, select him, then choose the symbol of what you want him to do the most. Remember to give doctors special positions. Assign one doctor to run the GP's Office. Get another doctor with psychiatry experience and make him your psychiatrist. This helps because if the GP's Office Doctor goes to rest, the Psychiatrist Doctor can take over. Turn up the heat all the way, and look at your hospital map. Strategically place radiators to fill up any black spots. There is no way to fully eradicate the heat problem, but this at least stops them from complaining. For any VIPs that come around, try getting everyone cured as quickly as possible. Do not kill anyone, clean up any mess with the Soda Machine trick, and try to get your doctors as rested up as possible so that they do not look angry. The highest positive response you can receive from a VIP is "That's a Super Hospital. And I should know, I've been in a few." You also get a $1,500 cash grant. In later levels, things might start getting busy. When starting a new level that you know is going to get hectic, set a space for two reception desks side by side and hire the receptionists for them. Put two GP's Offices side by side as well, and hire two doctors to head it up. In case there is a rush, you will have more open diagnosis available. Never guess on the cure; this will kill patients if you are wrong. Save the game when one of the little green question marks appear (turn off autosave so this does not cause problems), then take a guess at the cure. If the patient gets cured, great job. If he dies, load the game from the previous file and send the patient home. By doing this, you can cure who you can, and prevent deaths at the same time.
-During an emergency, save the game before selecting the icon. See what it is and what the status of those doctors and rooms are. Then, load the saved game and set it on the slowest speed. Get your doctors in the correct place (for example, rest them up a bit in the staff room first or put them in the room needed for the emergency) before you select the icon. It is also a good idea for the emergencies which take a while and have more than six people to have two rooms ready (for example, Psychiatric, Fracture Clinic, Slack Tongue room, etc.). If you have two rooms ready and they still go to only one, place a reception desk and receptionist by them and select the door for the room on which they are queuing. RIGHT CLICK on the people towards the back of the queue and send them to reception. She will then send them to the other room. This allows you to easily do the high amounts of people in the required time.