Find a hackable vending or health machine near a Bot Shutdown Panel. Hack the machine, and stop the pointer on the red to activate the alarm, thus triggering the Security Bots to come after you. Once you see them, quickly take a picture of one of them with the camera, then use the Bot Shutdown Panel to shut them down. The disabled bot will still be highlighted by the research camera, allowing you to research Security easily.
Before fighting the second Big Sister (if you are harvesting ADAM but saving the girls), you will get an Enrage Plasmid. There are two bodies to scrounge ADAM from. One is more easily securable, which has a security camera, a rocket launcher bot, and a large puddle of water in this area. The Big Daddy comes back several times. If you drop off the little girl in her hole near here, you can wait for the Big Sister to show up. Then, enrage the Big Daddy so that he takes on and kills the Big Sister. Your only concern will be Splicers and the Big Daddy after he is done with the Big Sister.
To easily gain money, go to an area with a working slot machine. For example, in the Siren Alley level inside the Mermaids Lounge, go upstairs into the room on the right side of the balcony that contains the slot machines. As you enter the room, turn left, and play the right-hand machine of the two that are facing you. Save the game before you start, and resave it every time your total money increases above where you started. If the machine does not payout after about a dozen turns, reload your saved game. It is possible to max out your wallet in around ten minutes. Repeat as desired.
Get your first Little Sister in Ryan Amusements. She will take you back into the main hall of Ryan Amusements to collect ADAM. While she is collecting ADAM, Splicers will attack and break down the door to the next section. Go through the door to find a desk on the left with an animatronic Andrew Ryan behind it. Near a cabinet that is behind him is a golf club. Use Telekinesis to pick up the club, then shoot it at the Andrew Ryan animatronic.
Rank 30 Tonic: Fast Feet Mask: Peacock Feather/Sun God Melee: Crowbar/Flashlight
Rank 31 Upgrade: Machine Gun Kickback Reduction
Rank 32 Tonic: Deadly Machine
Rank 33 Upgrade: Grenade Launcher Velocity Boost
Rank 34 Tonic: Headhunter
Rank 35 Upgrade: Crossbow Rate of Fire
Rank 36 Tonic: Big Game Hunter
Rank 37 Upgrade: Nail Gun Damage Increase
Rank 38 Tonic: Death Trap
Rank 39 Upgrade: Elephant Gun Damage Increase
Rank 40 Tonic: Resurrection Mask: Octopus/Demon Melee: Hatchet Final battle strategy:Fully research the Houdini Splicer and have the Natural Camouflage equipped. Just before the final battle, remain idle to become invisible. No one will attack. Do not move or you will become visible again, everything will attack, and you cannot turn invisible while being hit. Eleanor will eventually say she can fight--quickly summon her. She will distract and fight everyone, allowing you to turn invisible. She will eventually kill everyone so that you can escape.
To pull normal items toward you with Telekinesis and without using any Eve, do the following. Eve is only used when you release the button to throw an item with Telekinesis. Use Telekinesis to pull items such as ammunition or first aid kits toward you to collect without wasting any of your Eve. If you take an item you are already maxed out of, you will either be stuck holding it with Telekinesis or have to release the button to throw it and use some Eve. However, if you display the Plasmid wheel and select another Plasmid attack, you can release the button to drop the item without Telekinesis automatically throwing it. Thus, you will not use any Eve by dropping an item you cannot carry. This can also be used when pulling electrified trip wires out of walls. To do this, pull the item toward you with Telekinesis, and without releasing the trigger, display the Plasmid wheel to select another plasmid. When you close the Plasmid wheel and release the trigger, you will drop the item.
When bringing an item to you that you do not want to throw, and therefore keep from having to use your EVE, press Square to drop the object or press X to take the item if it can go into your inventory.
Unlock the following alternate endings by performing the corresponding tasks:
HOW TO UNLOCK
Bad ending #1
Save at least one Little Sister, and harvest at least one Little Sister. Choose to live at the end, and spare Grace Holloway, Stanley Poole, and Gilbert Alexander. Alternately, harvest all Little Sisters you adopt, and spare Grace Holloway, Stanley Poole, and Gilbert Alexander.
Bad ending #2
Save at least one Little Sister, and harvest at least one Little Sister. Choose to live at the end, and kill Grace Holloway, Stanley Poole, or Gilbert Alexander. Alternately, harvest all Little Sisters you adopt, and kill Grace Holloway, Stanley Poole, or Gilbert Alexander.
Good ending #1
Save all Little Sisters you adopt, and spare Grace Holloway, Stanley Poole, or Gilbert Alexander.
Good ending #2
Save all Little Sisters you adopt, and kill Grace Holloway, Stanley Poole, and Gilbert Alexander.
Standard ending #1
Save at least one Little Sister, and harvest at least one Little Sister. Choose to die at the end, and spare Grace Holloway, Stanley Poole, and Gilbert Alexander.
Standard ending #2
Save at least one Little Sister, and harvest at least one Little Sister. Choose to die at the end, and kill Grace Holloway, Stanley Poole, or Gilbert Alexander.
To easily gain XP in Multiplayer mode, have a friend join your game while it is in progress on any team-based game, putting him or her on the other team. Find a turret anywhere in the map, and make sure there is nobody around. You and your friend can hack the turret back and forth for 10 XP per hack. Repeat as desired.