Hitting enemies with guns glitch
Note: Doing this may freeze the game. Press the button to activate V.A.T.S. while simultaneously switching weapons set on a hotkey. For example, if you are wielding a hammer and you have a gun set to a hotkey, activate V.A.T.S. and you will hit a person with the gun equipped as if it was the hammer. You can use this to hit people with the rifle or even a bottle cap mine.