Recruit Morinth to get the Dominate skill and get a decent amount of Element Zero. Buy the Advanced Training upgrade and choose Dominate. This result in a bonus skill point, which is then used by the Retrain Powers upgrade. Repeat as desired to continue gaining skill points.
Walk around the ship in between missions to hear some funny quotes:
Stand near Jeff "Joker" Moreau (the pilot) without interacting with him. You will hear him say things such as the following:
"Why is it always claws and guns? Can't we piss off a fuzzy planet? Still dangerous, I know. But hey, bunnies." "Two years and everything hits the crapper. That'll teach you to die on me." "You know what I hate about deep space? Crap radio stations from two centuries back. My gosh, we were idiots."
Stand next to the two engineers near the Mass Effect Core to hear the the following:
Engineer Daniels: "Did you know we're sharing our deck with a krogan?" Engineer Donnelly: "Well that's just peachy."
There are three "Rich" mining planets with lots of materials. Go to the Micah system in the Vallhallan Threshold, and look for the three planets in the asteroids. Move the pointer to the left or right of the planet you wish to scan. Press Left Analog-stick and Right Analog-stick in the same direction to double the spin speed of the planet and allow you to locate resources on the grid line quickly.
During the Freedom's Progress mission, when you are told to place your teammates around the giant blast door, you can trick the game into spawning extra YMIR Mechs. First, position your team accordingly and watch the cutscene. You'll now face a Giant YMIR Mech. Instead of killing it, turn around, and head BACK through the blast door. This will glitch the game back before the cutscene. Place your team around the blast door again, and the cutscene will play. This will spawn an extra YMIR Mech. Repeat as many times as desired, but more than three YMIR Mechs will most likely kill you.
Space Hamster is available on Illium. Once you enter your cabin and select him, he comes out and does the same "Squeek" that Boo did, who was Minsc's "Intergalactic Space Hamster" from Baldur's Gate and Baldur's Gate 2.
Dominate is an excellent Biotic ability that allows you to control organic enemies and turn them into allies, similar to the Hack ability that controls synthetics. In order to get this ability as a Loyalty mission bonus to use for your character, help Morinth kill Samara during the latter's loyalty mission. However, if you want to keep Samara on your team but still have Morinth's Dominate ability, use the following trick. Play Samara's loyalty mission up to the point where Samara confronts Moritnth. Save the game right before the confrontation. When it is time to select who you will eliminate, choose the option that lets Morinth get the upper-hand on Samara and kill her. Create a separate saved game file. Go to the ship and talk to Morinth. Load the previous saved game then have Samara kill Morinth. You now get to keep Samara as a squad mate and have Morinth's Dominate ability when you choose a bonus loyalty power to add to your character in the prototype upgrade screen.
Unlock the following bonuses by completing the corresponding party member's Loyalty missions. You will also unlock their individuals skills for Shepard, alternate costumes, and increase the chance for surviving the suicide mission. Note: Complete the Advanced Training research upgrade for your ship to be able to select the skills:
Armor Piercing Ammo
Archangel's Loyalty mission.
Jacob's Loyalty mission.
Kill Samara during her Loyalty mission and have Morinth replace her.
The Dominate skill, the Retrain Powers and Advanced Training upgrades, and plenty of Element Zero are required. You can get the Dominate Skill by recruiting Morinth (Samara's daughter), which means you must sacrifice Samara in her own loyalty mission. A list of planets with Element Zero can be found below. First, buy Advanced Training and choose Dominate. This will land you a bonus skill point, which you can use by instituting the Retrain Powers upgrade. Repeat as desired.
To mine quicker, do not hold LT while scanning a planet. Instead, repeatedly tap LT until a blip appears on the scanner. Then, go back over the area while holding LT to find the best location to send the probe.
Notice after you press Y, the planet information screen on the right will tell you if the scan of planet reveals if it is "Rich", "Moderate", or "Poor". Rich planets usually give about 10+ good scan for ores. Ore yields vary from 1,500 to 3,000. Moderate will give about 8+ good scans, but around 35% to 55% yield compared to rich planets. Poor will give 5+ scans with yields 5% to 25% compared to rich planets. Note: If there is an anomaly on the planet (usually a rich planet) and you land before you scan, usually the Star Map on the Normandy will put you in a strange location away from the anomaly planet. Go back and rescan to get your ores.
For slightly faster planet scanning, put the scanner all the way to the right or left and rotate the planet the same way. The planet will spin quite a bit faster that way; simply push both sticks in the same direction. Start at the top of the planet and "peel" it like an electric apple peeler.
To gain more Paragon points during conversations, press LT when wings appear at the top left of the screen. To gain more Renegade points, press RT when a star appears.
To easily gain Paragon and Renegade points, unlock training to be able to redistribute your skill points. Talent Mastery will add a specific percentage to your Paragon and Renegade points. Respec and distribute them into your Mastery repeatedly until your Paragon and Renegade are full.
To unock the Dr. Pepper bonus items, go to http://www.drpepper.com/promotions/ea/signin/, and register for an account. You can register three different accounts to redeem three different codes and get each bonus item. Enter one of the following redemption codes, and select the "No Purchase" option:
Choose the "Redeem" button to get a login for an EA account. Log in with your EA account information that is linked to Mass Effect 2. Select Mass Effect 2 from the game list, and select the desired bonus item. Repeat the steps with a new drpepper.com account to get the other bonus items.
The following armor pieces will become available for purchase throughout the game:
N7 Helmet - +5% health N7 Breather Helmet - +5% health Kuwashii Visor - +10% headshot damage; at Omega Death Mask - +10% negotiation bonus; at Tuchanka Umbra Visor - +5% power damage; requires linking Dr. Pepper bonus code to EA account Recon Hood - +5% weapon damage; requires linking Dr. Pepper bonus code to EA account Sentry Interface - +5% shield strength; requires linking Dr. Pepper bonus code to EA account
N7 Shoulder Guards - +3% weapon damage Amplifier Plates - +5% power damage; at Illium Strength Boost Pads - +25% melee damage; at Omega Asymmetric Defense Layer - +5% health; at Tuchanka
N7 Chestplate - +5% power damage Capacitor Chestplate - -10% shields regeneration delay; at Citadel, Illium, or Omega Aegis Vest - +5% health; at Citadel Shield Harness - +5% shields; at Tuchanka
N7 Gauntlets - +3% health Heavy Damping Gauntlets - +5% shields ; at Tuchanka Off-Hand Ammo Pack - +10% spare ammo capacity; at Citadel Stabilization Gauntlets - +5% weapon damage; at Omega
N7 Greaves - +3% shield strength Stimulator Conduits - +10% storm speed; at Omega Life Support Webbing - +10% health; at Citadel Ordinance Packs - +10% spare heavy weapon ammo; at Omega
At the end of the game, examine the terminal that has all your teammates' dossiers. Read Legion's dossier to find out that he is a gamer. It will list the games that he has downloaded, his leaderboard scores, and other information about his gaming past.
If you chat it up with Yeoman Kelly Chambers often and choose to be kind to her you can instigate an "unusual" romantic encounter. You'll eventually be able to invite her to dinner. Additionally, you cannot let Kelly die in the final mission (choose a loyal escort for the crew in the final scene). After you beat the game, talk to Kelly and you'll receive an email from her. Go to your quarters and you'll be able to invite her up using your console. She'll appear and you'll be able to watch the evening's awkward events unwind. She's no Yeoman Rand, but she'll do.
To find easy mining planets, go to the Micah system in the Vallhallan Threshold and find the three planets hidden in the asteroids. They are all "Rich" planets with a lot of materials that will help with upgrades.
To get the Pulse Rifle, switch to Hardcore difficulty setting before landing on the planet. Complete Tali'Zora's recruitment mission. The Geth Pulse Rifle will be in the room where you find Tali. Then, change the difficulty back to your original setting.
If you completed the game but someone died after the landing on the Collector Ship, select someone else. On the final part where you select for the last time, do not take someone without loyalty (e.g. you lose it after you have completed their loyalty mission) as they will not survive. Instead, leave them with loyal company. For example, if you lose Tali's loyalty and take her through the final part of the mission and she dies, reload the game and leave her with everyone else. You can then get the achievement.
Any Biotic that lifts your enemy off the ground and the Cryo Bomb tech are required. with the Biotic, lift your enemy off the ground and hit him with the Cryo Bomb while he is still under the Biotic's effect. This will cause him to be stuck in a permanent falling state, where he is incapable of inflicting any damage. This is incredibly useful when attempting to prevent the deployment of Harbinger, because once he enters the glitched body he cannot move. By doing this, you can kill him at the end of a fight to prevent him from jumping to another body.
When asking Zaal'Koris about his funny name/ship name the "Qwib Qwib" (on the Quarian fleet vessel), the real joke is when he mentions desiring a more respectable ship name like "Defrahnz" or "Iktomi." These two names would have resulted in the following Quarian names: Zaal'Koris vas Defrahnz (vas deferens) and Zaal'Koris vas Iktomi (vasectomy).
How do you get loyalty missions to become available?
Answer from theFIFAking
Speak with the characters between each mission. It seems that most of the Loyalty missions get unlocked after you get your first 4 people (Grunt, Jack, Garrus/Archangel, Mordin). Simply keep using the "Talk about you" option on the characters between miss
By scanning planets. Press Y to observe them, then hold LT while watching the Richter scale on the top right of the screen. When the bars are high it indicates that there are resources there. Then press RT (i think) to release a probe and collect.